Evaluate Scientific Evidence Of The Association Between Temporomandibular Joint Disorders And Facial Asymmetry: A Systematic Review And Meta-Analysis

Abstract

Background and aim: clinical investigation of temporomandibular joint (TMJ) in asymmetric patients should be considered, even in the absence of signs and symptoms of TMJ disorders. Despite the importance of this issue, there is still no scientific evidence for a link between TMJ and FA disorders. Therefore the aim of current Systematic Review and Meta-Analysis study was evaluate Scientific Evidence of the Association between Temporomandibular Joint Disorders and Facial Asymmetry.

Method: From the electronic databases, PubMed, Scopus, LILACS, Web of Science, EBSCO, LIVIVO, and Embase have been used to perform a systematic literature over the last ten years between 2011 and May 2021.  For Data extraction, two reviewers blind and independently extracted data from abstract and full text of studies that included. Mean difference with 95% confidence interval (CI), fixed effect model and Inverse-variance method were calculated. Random effects were used to deal with potential heterogeneity and I² showed heterogeneity. I² values above 50% signified moderate-to-high heterogeneity. The Meta analysis have been evaluated with the statistical software Stata/MP v.16 (The fastest version of Stata).

Result: 610 studies were selected to review the abstracts, the full text of 14 studies was reviewed. Finally, four studies were selected. Mean difference of linear menton deviation (general and unilateral)) was (MD, 1.29 95% CI 0.31, 2.53. P<0.05) and (MD, 2.35 95% CI 1.57, 1.13; P<0.05), respectively; in TMJ group was greater than control group.

Conclusion: The present Systematic Review and Meta-Analysis study showed mean difference of linear menton deviation (general and unilateral)) in TMJ group was greater than control group, and mean of angular menton deviation (unilateral) in TMJ group was greater than control group.