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The current study computes (Karnatak College Dharwad) indices for the drugs used to treat COVID-19 using polynomials through edge partition technique for considered molecular structures of ivermectin, remdesivir and amphotericin B. Additionally, attention is focused on QSPR/QSAR (quantitative structure property/activity relationship) analysis of these and other drugs to investigate the correlation of their physicochemical properties using degree based topological indices. The conducted study reveals that the considered topological indices show strong positive correlation with the physicochemical properties of analysed drugs used to treat COVID-19 and mucormycosis. The appealing result is the performance of Randić index for mild disease category and black fungus disease, along with first index for moderate/severe disease category showing highest average correlation values for physicochemical properties of these drugs.
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