Evaluate The Clinical Outcomes Of Postoperative Atrial Fibrillation In Patients With Cardiac Surgery: Systematic Review And Meta-Analysis

Abstract

Background and aim: the aim of current Systematic review and meta-analysis study was evaluate the clinical outcomes of postoperative atrial fibrillation in patients with cardiac surgery.

Methods: From the electronic databases, PubMed, Scopus, Web of Science, EBSCO and Embase have been used to perform a systematic literature over the last ten years between 2011and September 2021. Odds ratio with 95% confidence interval (CI), fixed effect model and Mantel-Haenszel method were calculated. The Meta analysis have been evaluated with the statistical software Stata/MP v.16 (The fastest version of Stata).

Results: 2153 studies were selected to review the abstracts, the full text of 124 studies was reviewed. Finally, thirteen studies were selected. One-year, five years and ten years mortality in patients with postoperative atrial fibrillation was 14.09%, 8.43% and 17.65%; Odds ratio of overall mortality and Overall stroke was (OR, 0.76 95 % CI 0.67, 0.05; p=0.00) and (OR, 1.40 95 % CI 0.26, 2.53; p=0.02), respectively.

Conclusions: In patients with cardiac surgery that after surgery develop POAF, in the first year, the risk of death and stroke is much higher than patients without POAF. As a result, POAF is a significant change in the outcome of heart surgery.