Evaluation of In-Vitro free Radical Scavenging Potential of Whole Plant of Ziziphusxylopyrus Retz.

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M.Prabhu, G.Alagumanivasagam, Sureshkumar R.B

Abstract

The antioxidant activity of the entire plant of Ziziphusxylopyrus Retz. was studied in this study using several in-vitro techniques. Total antioxidant activity (Phosphomolybdic acid technique), FRAP test with reference standard ascorbate, and total flavonoids concentration were utilised to assess antioxidant activity. The total antioxidant activity of the ethanolic extract of Ziziphusxylopyrus Retz was determined to be modest. The IC50 values of the ethanolic extract of Ziziphusxylopyrus Retz and ascorbate were found to be 470μg/ml and 410μg/ml respectively. The ethanolic extract of Ziziphusxylopyrus Retz was found moderate effective in FRAP assay. However, as compared to the ethanolic extract containing ascorbate (standard), the Ziziphusxylopyrus Retz ethanolic extract performed better. There are a lot of flavonoids in the ethanolic extract of Ziziphusxylopyrus Retz. Furthermore, the findings were shown to be concentration dependant. All of the in-vitro tests show that the ethanolic extract of Ziziphusxylopyrus Retz has higher antioxidant activity. These in-vitro tests show that this plant extract is a greater source of natural antioxidants, which may aid in the prevention of different oxidative stresses.

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